Nix

NIX offers over-the-counter head lice treatments trusted by families and healthcare providers. NIX products deliver effective, easy-to-use solutions that include lice removal combs and target both lice and their eggs (nits).

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Buy NIX products online in Canada 

NIX is a trusted over-the-counter brand that specializes in head lice treatment and prevention solutions, developed to provide effective, accessible care for families and healthcare providers. NIX is best known for its core ingredient, permethrin, a synthetic pyrethroid insecticide, as well as newer pesticide-free formulations. NIX is manufactured and marketed by Prestige Consumer Healthcare Inc., a publicly traded U.S.-based company founded in 1996 and headquartered in Tarrytown, New York. The NIX product line first gained prominence in the late 1980s, when it was introduced to the North American market as a safe and effective FDA-approved lice treatment featuring permethrin 1%, a synthetic pyrethroid insecticide known for its ability to kill lice and their eggs (nits) with one application.

Over the years, NIX has become one of the most pharmacist-recommended lice treatment brands in North America. Its success is rooted in clinical validation, product reliability, and user-friendly packaging that often includes a nit-removal comb. These features help ensure a complete, step-by-step approach to lice removal, making it a go-to brand in both home and clinical settings. The original permethrin-based NIX Crème Rinse continues to be a frontline solution, but as concerns about lice resistance to pesticides have increased, NIX has diversified its portfolio. NIX’s current portfolio includes traditional permethrin-based lice treatments, as well as newer innovations such as NIX Ultra Lice Treatment Kit and NIX Ultra Super Lice Treatment, which use dimethicone and isoparaffin—physical, non-toxic agents that kill lice by coating and smothering them, rather than relying on insecticides. This shift reflects growing concerns about lice resistance to permethrin and demand for safer, pesticide-free options. The NIX Ultra system is intended for children aged two years and older and includes a lice-removal comb.

NIX revolutionized head lice management in the 1980s and 1990s, offering a single-application solution with high rates of effectiveness. However, over time, the emergence of permethrin-resistant lice (“superlice”) has diminished its efficacy in some regions, prompting the development of alternative formulations. The newer, non-insecticidal NIX Ultra products are designed to kill both regular and resistant lice by physically suffocating them, addressing concerns about resistance and safety. NIX’s reputation is built on efficacy, safety, and convenience, making it a leading name in lice treatment protocols recommended by school nurses, dermatologists, and pediatricians.

In response to evolving consumer needs, NIX launched the NIX Ultra line, which features pesticide-free, silicone-based formulas such as dimethicone that work by physically coating and suffocating lice rather than disrupting their nervous system. This mechanical method of action is especially effective against lice that have developed resistance to traditional treatments. In addition to its core treatments, NIX now offers preventative sprays, lice-eliminating shampoos, and complete kits that include tools for nit removal and scalp cleansing. NIX products have been widely used in pediatric and household settings, and NIX’s name has become synonymous with lice treatment for generations. 

NIX remains one of the most recognized lice treatment brands in North America. Its products are regulated as OTC drugs (permethrin-based) and medical devices (dimethicone-based). NIX continues to innovate, responding to public health trends and consumer preferences for non-toxic, easy-to-use solutions.NIX is a leading American head lice treatment brand with a legacy of pharmaceutical innovation, shifting from insecticide-based to mechanical, pesticide-free solutions, and maintaining a strong presence in both traditional and modern lice care. By combining clinical science with user-centered design, NIX continues to provide dependable solutions for lice outbreaks—supporting families with the tools they need to manage infestations quickly and effectively while minimizing disruption to daily life.

Where to buy NIX products in Canada 

You can purchase NIX items over-the-counter in Canada from YesWellness, an online retailer specializing in health and wellness solutions. YesWellness offers a wide range of NIX products, including:

  • NIX Dermal Cream Permethrin Cream
  • NIX Premium Metal 2-Sided Comb
  • NIX Complete Lice Elimination Kit

YesWellness provides the following benefits when purchasing NIX items:

  • Free shipping on orders over a certain amount.
  • Detailed product information and customer reviews.
  • A 60-day return policy for most items (exceptions may apply).

As one of Canada's leading online sources for health and wellness items, YesWellness ensures that customers have access to high-quality NIX items with the convenience of online shopping and home delivery. Here's how you can buy NIX from YesWellness:

  1. Visit the YesWellness website.
  2. Browse the NIX collection.
  3. Select the desired NIX products.
  4. Add them to your cart.
  5. Proceed to checkout.
  6. Complete your purchase.
  1. Canada 1-10 business days after your order leaves the warehouse and is dependent on your region.
  2. United States 4-14 business days after your order leaves our warehouse.

    For more info, visit our shipping page.

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