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Zantac products work to provide fast and lasting relief from the discomfort and burning feeling associated with heartburn, indigestion, upset stomach, and sour stomach. The active ingredient ranitidine temporarily decreases the amount of acid your stomach produces during digestion. Zantac can be used as preventative measure or as treatment, allowing you to fight heartburn before and after symptoms appear. One of our most popular Zantac products is Zantac 150 Maximum Strength.