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Essiac are the makers of a herbal formula, developed by Nurse Rene Caisse in 1922, based on a Canadian Objiwa Native herbal tea. The name Essiac comes from the reverse spelling of Caisse's surname. The herbs included in the Essiac formulation are Burdock Root, Slippery Elm, Indian Rhubarb Root and Sheep Sorrel. The makers of Essiac also produce Tru-Pine a formula based on a blend of Pine Bark, Rosehips and Vitamin C.